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Historically, natural products have played a major role in the development of antibiotics. Their complex chemical structures and high polarity give them advantages in the drug discovery process. (...)
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Lactococcus lactis and Lactococcus cremoris are Gram-positive lactic acid bacteria widely used as starter in milk fermentations. Lactococcal cells are covered with a polysaccharide pellicle (PSP) (...)
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Long-term sedimentary infill of tide-dominated estuaries remains poorly understood. The main issue is the time-scale gap between the tidal process (hourly variations) and sedimentary layer (...)
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As connected objects become the norm for quality of life, network intrusion detection is more critical than ever. Over the past decades, several different datasets have been developed to tackle (...)
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Tamoxifen, the gold standard drug for endocrine therapy for breast cancer, modulates the phosphorylation status of the TAU protein in Alzheimer’s disease by inhibiting CDK5 kinase activity. Its (...)
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Introduction While crucial to ensuring the production of accurate and high-quality data—and to avoid erroneous conclusions—data quality control (QC) in environmental monitoring datasets is still (...)
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BackgroundProspective data about the risks of thrombotic and severe haemorrhagic complications during pregnancy and post partum are unavailable for women with antiphospholipid syndrome. We aimed (...)
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AIMS : Tricuspid regurgitation (TR) is associated with significant morbidity and mortality. Its independent prognostic role has been repeatedly demonstrated. However, this valvular heart (...)
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Abstract Aims The respective roles of oral anticoagulation or antiplatelet therapy following transcatheter aortic valve implantation (TAVI) remain debated. ATLANTIS is an international, (...)
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La 9e édition du colloque Didapro-DidaSTIC se situe dans la continuité des précédentes et les différents thèmes qui y ont été abordés sont à nouveau convoqués. L’enjeu est non seulement de poursuivre la (...)
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In urban and peri-urban areas, where waste management is more than ever a major issue, insect farming may be an ecological way to recycle bio-waste in a circular bioeconomy approach. Some insect (...)
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With an ever increasing number of connected devices, network intrusion detection is more important than ever. Over the past few decades, several datasets were created to address this security (...)
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Listeria monocytogenes ( Lm ) is a ubiquitous bacterium that causes listeriosis, a serious foodborne illness. In the nature-to-human transmission route, Lm can prosper in various ecological (...)
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In urban and peri-urban areas, where waste management is more than ever a major issue, insect farming may be an ecological way to recycle bio-waste in a circular bioeconomy approach. Some insect (...)
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In urban and peri-urban areas, where waste management is more than ever a major issue, insect farming may be an ecological way to recycle bio-waste in a circular bioeconomy approach. Indeed, (...)
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The numerous processes (superficial and deep) occurring on margins, their origins, consequences, interactions and quantifications are only very partially described and understood. The (...)
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A Correction to this paper has been published : https://doi.org/10.1038/s41467-021-23162-4
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Abstract Background Linking independent sources of data describing the same individuals enable innovative epidemiological and health studies but require a robust record linkage approach. We (...)
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Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and familial factors. About 50 common variants have been shown to modify BC risk for mutation carriers. All but (...)
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Objectives : To assess the contribution of whole-body magnetic resonance imaging (WBMRI) and bone scintigraphy (BS) in addition to skeletal survey (SS) in detecting traumatic bone lesions and (...)
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Les mammites demeurent une maladie d’importance en élevage laitier, tant par ses conséquences sur l’économie de la filière lait que celles sur le bien-être des vaches et l’utilisation d’antibiotiques. (...)
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Purpose : To evaluate the association between a previously published 313 variant-based breast cancer (BC) polygenic risk score (PRS313) and contralateral breast cancer (CBC) risk, in BRCA1 and (...)
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Les dernières recommandations internationales pour l’évaluation du statut HER2 dans les cancers du sein, basées sur vingt ans d’expérience et sur les résultats de nombreuses études cliniques, ont vu le (...)
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Background : Linking independent sources of data describing the same individuals enable innovative epidemiological and health studies but require a robust record linkage approach. We describe a (...)
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Background : Various observations have suggested that the course of COVID-19 might be less favourable in patients with inflammatory rheumatic and musculoskeletal diseases receiving rituximab (...)
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The Internet connection is becoming ubiquitous in embedded systems, making them potential victims of intrusion. Although gaining popularity in recent years, deep learning based intrusion (...)
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Sous des aspects immatériels, le numérique (tout secteur confondu) est aujourd’hui responsable de près de 4 % des émissions mondiales des gaz à effet de serre. La prise en compte des problématiques de (...)
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Le projet Aqui-FR vise à construire un outil de suivi, de prévision et de projections de la ressource en eau souterraine en France en s’appuyant sur les modélisations hydrogéologiques régionales (...)
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We present early XRD and STA of serpentine under elevated temperatures and controlled atmospheres.
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Background : Patients with COVID-19 pneumonia have an excess of inflammation and increased concentrations of cytokines including interleukin-1 (IL-1). We aimed to determine whether anakinra, a (...)
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Background : Ovarian cancer risk in BRCA1 and BRCA2 mutation carriers has been shown to decrease with longer duration of oral contraceptive use. Although the effects of using oral contraceptives (...)
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Algal polysaccharides constitute a diverse and abundant reservoir of organic matter for marine heterotrophic bacteria, central to the oceanic carbon cycle. We investigated the uptake of alginate, (...)
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Importance Severe pneumonia with hyperinflammation and elevated interleukin-6 is a common presentation of coronavirus disease 2019 (COVID-19). Objective To determine whether tocilizumab (TCZ) (...)
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Objectives : There is little known about the impact of SARS-CoV-2 on patients with inflammatory rheumatic and musculoskeletal diseases (iRMD). We examined epidemiological characteristics (...)
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Objective HCQ is an essential medication in SLE, proven to lengthen survival and reduce flares. Its use, however, is limited by its rare but severe ophthalmological complications. Here, we aimed (...)
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Pascal Leroux